Article

Prolonged airway explant culture enables study of health, disease, and viral pathogenesis

2024-02-05

Abstract excerpt

In vitro models play a major role in studying airway physiology and disease. However, the native lung’s complex tissue architecture and non-epithelial cell lineages are not preserved in these models. Ex vivo tissue models could overcome in vitro limitations, but methods for long-term maintenance of ex vivo tissue has not been established. We describe methods to culture human large airway explants, small airway exp...

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Literature Corpus work: 2c50000d-0492-5043-8a14-d4aea11128b3
DOI: 10.1101/2024.02.03.578756

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