Article
Development of a Three-Dimensional Bioengineering Technology to Generate Lung Tissue for Personalized Disease Modeling.
Stem cells translational medicine - 1 Feb 2017
Wilkinson Dan C, Alva-Ornelas Jackelyn A, Sucre Jennifer M S, Vijayaraj Preethi, Durra Abdo, Richardson Wade, Jonas Steven J, Paul Manash K, Karumbayaram Saravanan, Dunn Bruce, Gomperts Brigitte N
Abstract excerpt
Stem cell technologies, especially patient-specific, induced stem cell pluripotency and directed differentiation, hold great promise for changing the landscape of medical therapies. Proper exploitation of these methods may lead to personalized organ transplants, but to regenerate organs, it is necessary to develop methods for assembling differentiated cells into functional, organ-level tissues. The generation of...
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