Article
Infliximab-induced psoriasis and psoriasiform skin lesions in pediatric Crohn disease and a potential association with IL-23 receptor polymorphisms.
Journal of pediatric gastroenterology and nutrition - 1 May 2013
Sherlock Mary E, Walters Thomas, Tabbers Merit M, Frost Karen, Zachos Mary, Muise Aleixo, Pope Elena, Griffiths Anne M
Abstract excerpt
BACKGROUND: Infliximab (IFX), an established therapy for pediatric Crohn disease (CD), is also efficacious in treating psoriasis, a skin disorder, in which tumor necrosis factor-α is implicated pathogenically. Paradoxically, there have been numerous reports of new-onset psoriasis following tumor...
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