Article
Functional genomics of attention-deficit/hyperactivity disorder (ADHD) risk alleles on dopamine transporter binding in ADHD and healthy control subjects.
Biological psychiatry - 15 Jul 2013
Spencer Thomas J, Biederman Joseph, Faraone Stephen V, Madras Bertha K, Bonab Ali A, Dougherty Darin D, Batchelder Holly, Clarke Allison, Fischman Alan J
Abstract excerpt
BACKGROUND: The main aim of this study was to examine the relationship between dopamine transporter (DAT) binding in the striatum in individuals with and without attention-deficit/hyperactivity disorder (ADHD), attending to the 3'-untranslated region of the gene (3'-UTR) and intron8 variable number of tandem repeats (VNTR) polymorphisms of the DAT (SLC6A3) gene. METHODS: Subjects consisted of 68 psychotropic...
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