Article
Striatal dopamine transporter availability associated with polymorphisms in the dopamine transporter gene SLC6A3.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine - 1 Jan 2009
van de Giessen Elisabeth M, de Win Maartje M L, Tanck Michael W T, van den Brink Wim, Baas Frank, Booij Jan
Abstract excerpt
UNLABELLED: Polymorphisms in the dopamine transporter (DAT) gene SLC6A3 are associated with human striatal DAT expression, but the exact effects on DAT expression are not clear. A variable number of tandem repeats (VNTR) in the 3' untranslated region of the DAT gene was previously investigated in relation to striatal DAT availability, but the results were inconclusive. Other polymorphisms in the DAT gene were not...
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