Effect of dopamine transporter gene (SLC6A3) variation on dorsal anterior cingulate function in attention-deficit/hyperactivity disorder.

doi:10.1002/ajmg.b.31022

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Article

Effect of dopamine transporter gene (SLC6A3) variation on dorsal anterior cingulate function in attention-deficit/hyperactivity disorder.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Mar 2010

Brown Ariel B, Biederman Joseph, Valera Eve M, Doyle Alysa E, Bush George, Spencer Thomas, Monuteaux Michael C, Mick Eric, Whitfield-Gabrieli Susan, Makris Nikos, LaViolette Peter S, Oscar-Berman Marlene, Faraone Stephen V, Seidman Larry J

Abstract excerpt

Although attention-deficit/hyperactivity disorder (ADHD) is associated both with brain alterations in attention and executive function (EF) circuitry and with genetic variations within the dopamine system (including the dopamine transporter gene [SLC6A3]), few studies have directly investigated how genetic variations are linked to brain alterations. We sought to examine how a polymorphism in the 3' untranslated...

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PMID: 19676101
DOI: 10.1002/ajmg.b.31022
PMCID: PMC2915441

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