Article
Sequence variation in the human dopamine transporter gene in children with attention deficit hyperactivity disorder.
Neuropharmacology - 1 Nov 2005
Mazei-Robison Michelle S, Couch R Steven, Shelton Richard C, Stein Mark A, Blakely Randy D
Abstract excerpt
The activity of the presynaptic dopamine (DA) transporter (DAT) is critical in mediating the magnitude and duration of dopaminergic signaling in the brain. Multiple genetic studies have found an association between attention deficit hyperactivity disorder (ADHD) and a variable number tandem repeat (VNTR) in the 3'-untranslated region (3'VNTR) of the hDAT gene (SLC6A3), however none of these studies examined the...
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