Article
Lack of an association between two BER gene polymorphisms and breast cancer risk: a meta-analysis.
PloS one - 1 Jan 2012
Wu Bian, Liu Hong-Li, Zhang Sheng, Dong Xiao-Rong, Wu Gang
Abstract excerpt
BACKGROUND: The base excision repair (BER) pathway removes DNA damage caused by ionizing radiation, reactive oxidative species and methylating agents. ADPRT and APE1 are two important genes in the BER pathway. Several studies have evaluated the association between polymorphisms in the two BER genes (ADPRT Val762Ala and APE1 Asp148Glu) and breast cancer risk. However, the results are inconsistent....
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