Article
Polymorphisms of ADPRT Val762Ala and XRCC1 Arg399Glu and risk of breast cancer in Chinese women: a case control analysis.
Oncology reports - 1 Jan 2006
Zhai Xiangjun, Liu Jiyong, Hu Zhibin, Wang Shui, Qing Jianwei, Wang Xuechen, Jin Guangfu, Gao Jun, Wang Xinru, Shen Hongbing
Abstract excerpt
Adenosine diphosphate ribosyl transferase (ADPRT) and X-ray repair cross-complementing 1 (XRCC1) are two major base excision repair (BER) proteins and act cooperatively in the BER processes. Polymorphisms of ADPRT Val762Ala and XRCC1 Arg399Gln may alter their protein functions and BER activity, and were therefore hypothesized to be associated with breast cancer susceptibility. We examined the contributions of...
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