Article
Differential analysis of high-throughput quantitative genetic interaction data.
Genome biology - 26 Dec 2012
Bean Gordon J, Ideker Trey
Abstract excerpt
Synthetic genetic arrays have been very effective at measuring genetic interactions in yeast in a high-throughput manner and recently have been expanded to measure quantitative changes in interaction, termed 'differential interactions', across multiple conditions. Here, we present a strategy that leverages statistical information from the experimental design to produce a novel, quantitative differential...
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