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Article

Predicting quantitative genetic interactions by means of sequential matrix approximation.

PloS one - 26 Sept 2008

Järvinen Aki P, Hiissa Jukka, Elo Laura L, Aittokallio Tero

Abstract excerpt

Despite the emerging experimental techniques for perturbing multiple genes and measuring their quantitative phenotypic effects, genetic interactions have remained extremely difficult to predict on a large scale. Using a recent high-resolution screen of genetic interactions in yeast as a case study, we investigated whether the extraction of pertinent information encoded in the quantitative phenotypic measurements...

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Identifiers

PMID: 18818762
DOI: 10.1371/journal.pone.0003284
PMCID: PMC2538561

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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