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Article

Genetic Interaction Score (S-Score) Calculation, Clustering, and Visualization of Genetic Interaction Profiles for Yeast.

Cold Spring Harbor protocols - 1 Feb 2018

Roguev Assen, Ryan Colm J, Xu Jiewei, Colson Isabelle, Hartsuiker Edgar, Krogan Nevan

Abstract excerpt

This protocol describes computational analysis of genetic interaction screens, ranging from data capture (plate imaging) to downstream analyses. Plate imaging approaches using both digital camera and office flatbed scanners are included, along with a protocol for the extraction of colony size measurements from the resulting images. A commonly used genetic interaction scoring method, calculation of the S-score, is...

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PMID: 28733406
DOI: 10.1101/pdb.prot091983

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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