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Article

Pneumocystis jirovecii genotype associated with increased death rate of HIV-infected patients with pneumonia.

Emerging infectious diseases - 1 Jan 2013

Rabodonirina Meja, Vaillant Laetitia, Taffé Patrick, Nahimana Aimable, Gillibert René-Pierre, Vanhems Philippe, Hauser Philippe M

Abstract excerpt

Pneumocystis jirovecii dihydropteroate synthase (DHPS) mutations have been associated with failure of sulfa prophylaxis; their effect on the outcome of patients with P. jirovecii pneumonia (PCP) remains controversial. P. jirovecii DHPS polymorphisms and genotypes were identified in 112 cases of PCP in 110 HIV-infected patients by using PCR single-strand conformation polymorphism. Of the 110 patients observed, 21...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Trimethoprim, Sulfamethoxazole Drug Combination

Source

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Identifiers

PMID: 23260763
DOI: 10.3201/eid1901.120140
PMCID: PMC3557975

Genes

DHPS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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