Article
Treatment of Pneumocystis jirovecii pneumonia in HIV-infected patients: a review.
Expert review of anti-infective therapy - 1 Sept 2017
Huang Yu-Shan, Yang Jen-Jia, Lee Nan-Yao, Chen Guan-Jhou, Ko Wen-Chien, Sun Hsin-Yun, Hung Chien-Ching
Abstract excerpt
INTRODUCTION: Pneumocystis pneumonia is a potentially life-threatening pulmonary infection that occurs in immunocompromised individuals and HIV-infected patients with a low CD4 cell count. Trimethoprim-sulfamethoxazole has been used as the first-line agent for treatment, but mutations within dihydropteroate synthase gene render potential resistance to sulfamide. Despite advances of combination antiretroviral...
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