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Article

CYP2C192 and 17 alleles have a significant impact on platelet response and bleeding risk in patients treated with prasugrel after acute coronary syndrome.

JACC. Cardiovascular interventions - 1 Dec 2012

Cuisset Thomas, Loosveld Marie, Morange Pierre Emmanuel, Quilici Jacques, Moro Pierre Julien, Saut Noémie, Gaborit Bénédicte, Castelli Christel, Beguin Shirley, Grosdidier Charlotte, Fourcade Laurent, Bonnet Jean-Louis, Alessi Marie-Christine

Abstract excerpt

OBJECTIVES: The present study was designed to assess the effect of genetic variants on chronic biological response to prasugrel and bleeding complications. BACKGROUND: CYP2C19*2 loss-of-function allele and CYP2C19*17 gain-of-function allele have been linked with response to clopidogrel, but preliminary data did not show any significant influence of these alleles on prasugrel effect. METHODS: A total of 213...

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Identifiers

PMID: 23257377
DOI: 10.1016/j.jcin.2012.07.015

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VASP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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