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Article

The influence of CYP2C192 and 17 on on-treatment platelet reactivity and bleeding events in patients undergoing elective coronary stenting.

Pharmacogenetics and genomics - 1 Mar 2012

Harmsze Ankie M, van Werkum Jochem W, Hackeng Christian M, Ruven Hendrik J T, Kelder Johannes C, Bouman Heleen J, Breet Nicoline J, Ten Berg Jurriën M, Klungel Olaf H, de Boer Anthonius, Deneer Vera H M

Abstract excerpt

OBJECTIVES: To investigate the impact of genotypes on the basis of the loss-of-function variant CYP2C19*2 and the gain-of-function variant CYP2C19*17 on on-treatment platelet reactivity and on the occurrence of Thrombolysis in Myocardial Infarction (TIMI) major bleedings in 820 clopidogrel-treated patients who underwent elective coronary stenting. METHODS: On-treatment platelet reactivity was quantified using...

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PMID: 22228204
DOI: 10.1097/FPC.0b013e32834ff6e3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The influence of CYP2C19*2 and *17 on on-treatment platelet reactivity and bleeding events in patients undergoing elective coronary stenting.PMID 22228204Read ↗

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