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Article

Impact of genetic variants on post-clopidogrel platelet reactivity in patients after elective percutaneous coronary intervention.

Pharmacogenomics - 1 Sept 2011

Rideg Orsolya, Komócsi András, Magyarlaki Tamás, Tokés-Füzesi Margit, Miseta Attila, Kovács Gábor L, Aradi Dániel

Abstract excerpt

AIM: To determine the effect of various SNPs on post-clopidogrel platelet reactivity and clinical outcome. MATERIALS & METHODS: Cytochrome 2C19 (CYP2C19) loss-of-function (LOF; *2, *3) and gain-of-function (GOF; *17) allelic variants, together with ABCB1 (3435 C→T and 2677 G→T/A) and paraoxonase-1 (PON-1; 192 Q→R) SNPs were analyzed in 189 patients after elective stent implantation who participated in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter, Subfamily B

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Source

Identifiers

PMID: 21806387
DOI: 10.2217/pgs.11.73

Genes

ABCB1
VASP

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