Article
Influence of CYP2C19 polymorphisms in platelet reactivity and prognosis in an unselected population of non ST elevation acute coronary syndrome.
Revista espanola de cardiologia (English ed.) - 1 Mar 2012
Tello-Montoliu Antonio, Jover Eva, Marín Francisco, Bernal Agustina, Lozano María L, Sánchez-Vega Beatriz, Pastor Francisco J, Hurtado José A, Valdés Mariano, Vicente Vicente, Rivera José
Abstract excerpt
INTRODUCTION AND OBJECTIVES: CYP2C19*2 and CYP2C19*17 alleles appear to contribute to heterogeneous clopidogrel metabolism. The aims of the present study were to assess the phenotype-genotype relationship of CYP2C19*2 and *17 allele carriage and to explore the clinical impact of those polymorphisms at 6-month follow-up of an acute event in an unselected population of non-ST elevation acute coronary syndrome....
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