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Article

Effect of CYP2C192 and 17 genetic variants on platelet response to clopidogrel and prasugrel maintenance dose and relation to bleeding complications.

The American journal of cardiology - 1 Apr 2013

Grosdidier Charlotte, Quilici Jacques, Loosveld Marie, Camoin Laurence, Moro Pierre Julien, Saut Noémie, Gaborit Bénédicte, Pankert Mathieu, Cohen William, Lambert Marc, Beguin Shirley, Morange Pierre Emmanuel, Bonnet Jean-Louis, Alessi Marie-Christine, Cuisset Thomas

Abstract excerpt

The present study was performed to compare the influence of cytochrome P459 2C19 (CYP2C19) *2 and *17 genetic variants on the platelet response to clopidogrel and prasugrel maintenance therapy and to assess the relation between platelet reactivity and bleeding complications. A total of 730 patients were included (517 patients treated with clopidogrel 150 mg/day and 213 discharged with prasugrel 10 mg). Platelet...

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Source

Identifiers

PMID: 23340030
DOI: 10.1016/j.amjcard.2012.12.013

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VASP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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