Article
Prasugrel overcomes high on-clopidogrel platelet reactivity post-stenting more effectively than high-dose (150-mg) clopidogrel: the importance of CYP2C19*2 genotyping.
JACC. Cardiovascular interventions - 1 Apr 2011
Alexopoulos Dimitrios, Dimitropoulos Gerasimos, Davlouros Periklis, Xanthopoulou Ioanna, Kassimis George, Stavrou Eleana F, Hahalis George, Athanassiadou Aglaia
Abstract excerpt
OBJECTIVES: The primary aim of the study was to determine the antiplatelet effects of prasugrel versus high-dose clopidogrel in patients with high on-treatment platelet reactivity (HTPR) after percutaneous coronary intervention (PCI) and, secondarily, their relation to cytochrome (CYP) 2C19*2 carriage. BACKGROUND: High on-treatment platelet reactivity after clopidogrel administration after PCI is linked to the...
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