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Identification of Cell Surface Proteins as Potential Immunotherapy Targets in 12 Pediatric Cancers

1 Jan 2012

Abstract excerpt

Technological advances now allow us to rapidly produce CARs and other antibody-derived therapeutics targeting cell surface receptors. To maximize the potential of these new technologies, relevant extracellular targets must be identified. The Pediatric Oncology Branch of the NCI curates a freely accessible database of gene expression data for both pediatric cancers and normal tissues, through which we have defined...

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PMID: 23251904
DOI: 10.3389/fonc.2012.00194

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