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Article

Human regulatory T cells of G-CSF mobilized allogeneic stem cell donors qualify for clinical application.

PloS one - 1 Jan 2012

Ukena Sya N, Velaga Sarvari, Goudeva Lilia, Ivanyi Philipp, Olek Sven, Falk Christine S, Ganser Arnold, Franzke Anke

Abstract excerpt

Recent clinical studies demonstrate the high potency of regulatory T cells (Tregs) to control graft-versus-host disease in hematopoietic stem cell transplantation (SCT). However, the adoptive transfer of Tregs is limited by their low frequency in unstimulated donors and considerable concerns that G-CSF induced SC mobilization might have negative effects on the stability and function of Tregs. The isolation of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23251603
DOI: 10.1371/journal.pone.0051644
PMCID: PMC3520921

Genes

SCT
CXCR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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