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Regulatory T cell therapy for Graft-versus-Host Disease

16 Apr 2025

Abstract excerpt

Graft-versus-Host Disease (GvHD) is the main cause of morbidity and mortality of allogeneic hematopoietic cell transplantation (allo-HCT). Conventional immunosuppressive pharmacotherapy remains the backbone of GvHD prevention and treatment with suboptimal outcomes especially for patients with refractory disease. Adoptive immunotherapy with regulatory T-cells (Treg) stands as an alternative approach that aims to...

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PMID: 40240498
DOI: 10.1038/s41409-025-02553-x

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