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Regulatory T Cell Therapy of Graft-versus-Host Disease: Advances and Challenges

7 Sept 2021

Abstract excerpt

Graft-versus-host disease (GVHD) is the leading cause of morbidity and mortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Immunomodulation using regulatory T cells (Tregs) offers an exciting option to prevent and/or treat GVHD as these cells naturally function to maintain immune homeostasis, can induce tolerance following HSCT, and have a tissue reparative function. Studies to date...

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Hematopoietic Stem Cell Transplantation
Immune Cell Function and Interaction
T-cell and B-cell Immunology

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34575843
DOI: 10.3390/ijms22189676

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