Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Efficient treatment of murine acute GvHD by in vitro expanded donor regulatory T cells.

Leukemia - 1 Mar 2020

Riegel Christin, Boeld Tina J, Doser Kristina, Huber Elisabeth, Hoffmann Petra, Edinger Matthias

Abstract excerpt

Acute graft-versus-host disease (aGvHD) is a frequent complication after allogeneic bone marrow/stem cell transplantation (BMT/SCT) induced by co-transplanted alloreactive conventional donor T cells. We previously demonstrated that the adoptive transfer of donor CD4+CD25+Foxp3+ regulatory T cells (Treg) at the time of BMT prevents aGvHD in murine models. Yet, the therapeutic potential of donor Treg for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow Cells
Share to Bone Marrow Transplantation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Graft vs Host Disease

Share to Immune System

Share to Inflammation

Share to Myeloid Cells

Share to T-Lymphocytes, Regulatory

Share to Transplantation, Homologous

Source

Open in PubMed Open full text

Identifiers

PMID: 31719679
DOI: 10.1038/s41375-019-0625-3
PMCID: PMC7214258

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Efficient treatment of murine acute GvHD by in vitro expanded donor regulatory T cells.PMID 31719679Read ↗

Regulatory T cell therapy for Graft-versus-Host DiseaseSemantic proximity Read ↗

Regulatory T Cell Therapy of Graft-versus-Host Disease: Advances and ChallengesSemantic proximity Read ↗

Frequency of CD4(+)CD25(hi)FOXP3(+) regulatory T cells has diagnostic and prognostic value as a biomarker for acute graft-versus-host-disease.Semantic proximity Read ↗

Ex vivo expanded human CD4+CD25+Foxp3+ regulatory T cells prevent lethal xenogenic graft versus host disease (GVHD)Semantic proximity Read ↗

Blockade of chronic graft-versus-host disease by alloantigen-induced CD4+CD25+Foxp3+ regulatory T cells in nonlymphopenic hosts.Semantic proximity Read ↗

Integrated Analysis of T cell Repertoire and Transcriptome Identifies Mechanisms of Regulatory T cell (Treg) Suppression of Acute Graft-versus-Host-DiseaseSemantic proximity Read ↗

CD8+ Foxp3+ Regulatory T Cells Are Induced during Graft-versus-Host Disease and Mitigate Disease SeveritySemantic proximity Read ↗

Identification and expansion of highly suppressive CD8(+)FoxP3(+) regulatory T cells after experimental allogeneic bone marrow transplantation.Semantic proximity Read ↗

CD4+CD25+ Immunoregulatory T CellsSemantic proximity Read ↗

Donor regulatory T cells rapidly adapt to recipient tissues to control murine acute graft-versus-host diseaseSemantic proximity Read ↗

Harnessing Advances in T Regulatory Cell Biology for Cellular Therapy in Transplantation.Semantic proximity Read ↗

Past, Present, and Future of Regulatory T Cell Therapy in Transplantation and AutoimmunitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.