Article
Analysis of nevirapine resistance in HIV-infected infants who received extended nevirapine or nevirapine/zidovudine prophylaxis.
AIDS (London, England) - 24 Apr 2011
Fogel Jessica, Hoover Donald R, Sun Jin, Mofenson Lynne M, Fowler Mary G, Taylor Allan W, Kumwenda Newton, Taha Taha E, Eshleman Susan H
Abstract excerpt
BACKGROUND: In the Post Exposure Prophylaxis of Infants (PEPI)-Malawi trial, infants received up to 14 weeks of extended nevirapine (NVP) or extended NVP with zidovudine (NVP + ZDV) to prevent postnatal HIV transmission. We examined emergence and persistence of NVP resistance in HIV-infected infants who received these regimens prior to HIV diagnosis. METHODS: Infant plasma samples collected at 14 weeks of age...
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