Article
Initiation of antiretroviral treatment in women after delivery can induce multiclass drug resistance in breastfeeding HIV-infected infants.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Apr 2011
Fogel Jessica, Li Qing, Taha Taha E, Hoover Donald R, Kumwenda Newton I, Mofenson Lynne M, Kumwenda Johnstone J, Fowler Mary Glenn, Thigpen Michael C, Eshleman Susan H
Abstract excerpt
BACKGROUND: The World Health Organization currently recommends initiation of highly active antiretroviral therapy (HAART) for human immunodeficiency virus (HIV)-infected lactating women with CD4+ cell counts <350 cells/μL or stage 3 or 4 disease. We analyzed antiretroviral drug resistance in HIV-infected infants in the Post Exposure Prophylaxis of Infants trial whose mothers initiated HAART postpartum (with a...
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