Article
Human Immunodeficiency Virus Antiretroviral Resistance and Transmission in Mother-Infant Pairs Enrolled in a Large Perinatal Study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 17 May 2018
Yeganeh Nava, Kerin Tara, Ank Bonnie, Watts D Heather, Camarca Margaret, Joao Esau C, Pilotto Jose Henrique, Veloso Valdilea G, Bryson Yvonne, Gray Glenda, Theron Gerhard, Dickover Ruth, Morgado Mariza G, Santos Breno, Kreitchmann Regis, Mofenson Lynne, Nielsen-Saines Karin
Abstract excerpt
Background: The presence of antiretroviral drug-associated resistance mutations (DRMs) may be particularly problematic in human immunodeficiency virus (HIV)-infected pregnant women as it can lead to mother-to-child transmission (MTCT) of resistant HIV strains. This study evaluated the prevalence and the effect of antiretroviral DRMs in previously untreated mother-infant pairs. Methods: A case-control design of...
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