Article
Genetic variability in platelet integrin α2β1 density: possible contributor to Plasmodium vivax-induced severe thrombocytopenia.
The American journal of tropical medicine and hygiene - 1 Feb 2013
Campos Fernanda M F, Santos Marina L S, Kano Flora S, Fontes Cor J F, Lacerda Marcus V G, Brito Cristiana F A, Carvalho Luzia H
Abstract excerpt
Understanding the pathogenesis of Plasmodium vivax malaria is challenging. We hypothesized that susceptibility to P. vivax-induced thrombocytopenia could be associated with polymorphisms on relevant platelet membrane integrins: integrin α2 (C807T), and integrin β3 (T1565C). Although β3 polymorphi...
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