Article
Platelet glycoprotein I(b)alpha and integrin alpha2 beta1 polymorphisms: gene frequencies and linkage disequilibrium in a population diversity panel.
Journal of thrombosis and haemostasis : JTH - 1 Jul 2005
Di Paola J, Jugessur A, Goldman T, Reiland J, Tallman D, Sayago C, Murray J C
Abstract excerpt
Genetic variants in the GP1BA and ITGA2 genes have been proposed as potential modifiers for arterial vascular disease and bleeding disorders. Since ancestry may play an important role in the prevalence of these variants, we sought to determine their allele frequency and linkage disequilibrium in a collection of 1064 DNA samples from 51 ethnic groups. We studied haplotypes of ITGA2 defined by single nucleotide...
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