Article
Clinical and functional consequences of platelet membrane glycoprotein polymorphisms.
Seminars in thrombosis and hemostasis - 1 Oct 2004
Yee Donald L, Bray Paul F
Abstract excerpt
The last several years have seen an abundance of studies of genetic risk factors for vascular disease, and platelet glycoprotein (GP) polymorphisms have been a primary focus of this area of research. This article reviews GP receptor polymorphisms, particularly those on GPIa-IIa (integrin alpha2beta1), GPIb-IX-V, GPIIb-IIIa (integrin alpha(IIb)beta3), and GPVI, and summarizes clinical and functional studies that...
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