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Article

Mean platelet volume and integrin alleles correlate with levels of integrins α(IIb)β(3) and α(2)β(1) in acute coronary syndrome patients and normal subjects.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jan 2012

Kunicki Thomas J, Williams Shirley A, Nugent Diane J, Yeager Mark

Abstract excerpt

OBJECTIVE: The interindividual variation in platelet α(2)β(1) exceeds a 2-fold variance in platelet α(IIb)β(3) level. Our objective was to parse the contribution of mean platelet volume (MPV) and integrin gene alleles to this variation in large cohorts of patients with acute coronary syndrome (ACS) and normal subjects. METHODS AND RESULTS: Platelet α(IIb)β(3) and α(2)β(1) levels were measured by flow cytometry in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22015659
DOI: 10.1161/ATVBAHA.111.239392

Genes

ITGA2
ITGB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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