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Article

Zizimin and Dock guanine nucleotide exchange factors in cell function and disease.

Small GTPases - 1 Jan 2000

Pakes Nicholl K, Veltman Douwe M, Williams Robin S B

Abstract excerpt

Zizimin proteins belong to the Dock (Dedicator of Cytokinesis) superfamily of Guanine nucleotide Exchange Factor (GEF) proteins. This family of proteins plays a role in the regulation of Rho family small GTPases. Together the Rho family of small GTPases and the Dock/Zizimin proteins play a vital role in a number of cell processes including cell migration, apoptosis, cell division and cell adhesion. Our recent...

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Identifiers

PMID: 23247359
DOI: 10.4161/sgtp.22087
PMCID: PMC3620097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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