Article
Loop-mediated isothermal amplification for detection of HLA-B*58:01 allele.
Tissue antigens - 1 Feb 2013
Kwok J, Kwong K M
Abstract excerpt
Strong association of human leukocyte antigen (HLA)-B*58:01 allele with allopurinol-induced hypersensitivity was found worldwide, especially in the Han Chinese populations. This study aims to develop and evaluate a loop-mediated isothermal amplification (LAMP) assay for rapid detection of HLA-B*58:01. Two sets of LAMP primers targeting exons 2 and 3 of HLA-B*58:01 allele were designed and their annealing...
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