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Article

Rapid and reliable genotyping of HLA-B*58:01 in four Chinese populations using a single-tube duplex real-time PCR assay.

Pharmacogenomics - 1 Jan 2016

Kang Xing, Chen Rong, Han Min, Liu Zhengbin, Liu Jinhui, Dai Penggao, Chen Chao, Wang Huijuan

Abstract excerpt

AIM: HLA-B*58:01 is strongly associated with allopurinol-induced severe cutaneous adverse reactions. This study aimed to develop a new and convenient method for HLA-B*58:01 genotyping and to investigate HLA-B*58:01 distribution in different Chinese populations. MATERIALS & METHODS: Combining of sequence-specific primers and TaqMan probe, a single-tube duplex real-time PCR assay for HLA-B*58:01 typing was...

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PMID: 26652271
DOI: 10.2217/pgs.15.160

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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