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Article

Detection of HLA-B*58:01, the susceptible allele for allopurinol-induced hypersensitivity, by loop-mediated isothermal amplification.

The British journal of dermatology - 1 Mar 2013

Kwok J, Kwong K M

Abstract excerpt

BACKGROUND: Allopurinol, a common medication for gout treatment, can cause rare but life-threatening severe cutaneous adverse reactions. A strong pharmacogenetic association of human leucocyte antigen (HLA)-B*58:01 with allopurinol-induced drug hypersensitivity has been reported, especially in the Han Chinese population. OBJECTIVES: To develop a rapid and simple loop-mediated isothermal amplification (LAMP) assay...

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Source

Identifiers

PMID: 23066948
DOI: 10.1111/bjd.12097

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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