Article
Rapid detection of HLA-A*31:01 allele in DNA and blood samples using loop-mediated isothermal amplification.
The British journal of dermatology - 1 Jul 2014
Cheung Y K, Kwok M, Chan E, Kwan P
Abstract excerpt
BACKGROUND: The human leucocyte antigen (HLA) allele, HLA-A*31:01, is a biomarker for adverse cutaneous reactions to carbamazepine, a first-line antiepileptic drug. OBJECTIVES: To develop a platform that can rapidly detect the HLA-A*31:01 allele in blood samples to facilitate pretreatment screeni...
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