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Article

Migfilin's elimination from osteoarthritic chondrocytes further promotes the osteoarthritic phenotype via β-catenin upregulation.

Biochemical and biophysical research communications - 11 Jan 2013

Gkretsi Vasiliki, Papanikolaou Vassilis, Dubos Stephanie, Papathanasiou Ioanna, Giotopoulou Nikolina, Valiakou Vaia, Wu Chuanyue, Malizos Konstantinos N, Tsezou Aspasia

Abstract excerpt

Osteoarthritis (OA) is a debilitating disease of the joints characterized by cartilage degradation but to date there is no available pharmacological treatment to inhibit disease progression neither is there any available biomarker to predict its development. In the present study, we examined the expression level and possible involvement of novel cell-ECM adhesion-related molecules such as Iintegrin Linked Kinase...

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PMID: 23237804
DOI: 10.1016/j.bbrc.2012.12.008
PMCID: PMC3764434

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ILK

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