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Article

Impact of tumor microenvironment and epithelial phenotypes on metabolism in breast cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2013

Brauer Heather Ann, Makowski Liza, Hoadley Katherine A, Casbas-Hernandez Patricia, Lang Lindsay J, Romàn-Pèrez Erick, D'Arcy Monica, Freemerman Alex J, Perou Charles M, Troester Melissa A

Abstract excerpt

PURPOSE: Cancer cells have altered metabolism, with increased glucose uptake, glycolysis, and biomass production. This study conducted genomic and metabolomic analyses to elucidate how tumor and stromal genomic characteristics influence tumor metabolism. EXPERIMENTAL DESIGN: Thirty-three breast tumors and six normal breast tissues were analyzed by gene expression microarray and by mass spectrometry for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23236214
DOI: 10.1158/1078-0432.CCR-12-2123
PMCID: PMC3684709

Genes

HGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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