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Bulk and single-cell transcriptome profiling reveal the metabolic heterogeneity in human breast cancers

7 Mar 2021

Abstract excerpt

An emerging view regarding cancer metabolism is that it is heterogeneous and context-specific, but it remains to be elucidated in breast cancers. In this study, we characterized the energy-related metabolic features of breast cancers through integrative analyses of multiple datasets with genomics, transcriptomics, metabolomics, and single-cell transcriptome profiling. Energy-related metabolic signatures were used...

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PMID: 33677091
DOI: 10.1016/j.ymthe.2021.03.003

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