Article
Genetic polymorphisms in the Fas and FasL genes are associated with epithelial ovarian cancer risk and clinical outcomes.
Gynecologic oncology - 1 Mar 2013
Li Yan, Hao Ya-li, Kang Shan, Zhou Rong-miao, Wang Na, Qi Bing-li
Abstract excerpt
AIM: In this study, we evaluated whether functional polymorphisms within the Fas and FasL genes were associated with the risk of developing epithelial ovarian cancer (EOC) and survival of patients with EOC. METHODS: A case-control study was performed in 342 EOC patients and 344 control women. The genotypes of three promoter region polymorphisms (Fas -1377G/A, -670A/G and FasL -844T/C) were determined using ligase...
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