Article
Quantitative assessment of the association between three polymorphisms in FAS and FASL gene and breast cancer risk.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2014
Wang Zexing, Gu Jun, Nie Weiwei, Xu Jing, Huang Guichun, Guan Xiaoxiang
Abstract excerpt
FAS and FAS ligand (FASL) play crucial roles in apoptotic signaling, and deregulation of this pathway may facilitate carcinogenesis. Studies on the association between the FAS/FASL polymorphisms (FAS-1377G/A rs2234767, FAS-670A/G rs1800682, and FASL-844C/T rs763110) and breast cancer risk have reported inconsistent results. Therefore, to characterize the relationship between those polymorphisms and breast cancer...
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