Article
Positive and negative functional interactions between promoter elements from different classes of RNA polymerase III-transcribed genes.
The EMBO journal - 1 Apr 1990
Parry H D, Mattaj I W
Abstract excerpt
Consensus tRNA gene promoter elements, A and B boxes, were introduced into the coding sequence of a Xenopus U6 gene. Combinations in which A and B boxes were coupled to wild-type or mutant U6 promoters were made. In this way information about both the functions of individual promoter elements and functional relationships between different classes of RNA polymerase III promoter element were obtained. Mutants in...
Topics
- Animals
- Base Sequence
- Cloning, Molecular
- DNA-Directed RNA Polymerases
- Genes
- Molecular Sequence Data
- Mutation
- Oligonucleotide Probes
- Oocytes
- Promoter Regions, Genetic
- RNA Polymerase III
