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Article

Inhibition of ghrelin signaling improves the reproductive phenotype of male ob/ob mouse.

Fertility and sterility - 1 Mar 2013

Zhu Chu-Chao, Zhang Hua, Zhang Jin-Shan, Li Zhen, Zhao Jie, Li Wei, Zhang Yuan-Qiang

Abstract excerpt

OBJECTIVE: To investigate whether ghrelin signaling is involved in the pathogenesis of male factor infertility induced by leptin deficiency. DESIGN: Experimental study. SETTING: University academic medical center. ANIMAL(S): Ten-week-old C57BL/6J mice and ob/ob mice. INTERVENTION(S): Western blotting, (quantitative) reverse transcription-polymerase chain reaction (qRT-PCR), immunohistochemistry, and in situ end...

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Source

Identifiers

PMID: 23232360
DOI: 10.1016/j.fertnstert.2012.11.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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