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Article

Effect of MLH1 -93G>A on gene expression in patients with colorectal cancer.

Medical oncology (Northwood, London, England) - 1 Sept 2014

Funck Alexandre, Santos Juliana C, Silva-Fernandes Isabelle J L, Rabenhorst Silvia H B, Martinez Carlos A R, Ribeiro Marcelo L

Abstract excerpt

The DNA repair machinery plays a key role in maintaining genomic stability by preventing the emergence of mutations. Furthermore, the -93G>A polymorphism in the MLH1 gene has been associated with an increased risk of developing colorectal cancer. Therefore, the aim of this study was to examine the expression pattern and effect of this polymorphism in normal and tumour samples from patients with colorectal cancer....

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Source

Identifiers

PMID: 25115745
DOI: 10.1007/s12032-014-0160-z

Genes

MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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