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Article

The association between MLH1 -93 G>A polymorphism of DNA mismatch repair and cancer susceptibility: a meta-analysis.

Mutagenesis - 1 Sept 2011

Pan Xin-Min, Yang Wen-Zhong, Xu Guo-Hui, Bai Peng, Qin Hao-Jie, Zhang Lu-Shun, Zhai Xian-Dun, Tang Ming, Deng Wei, Zhang Lin, Gao Lin-Bo

Abstract excerpt

DNA mismatch repair, known as a fundamentally biological pathway, plays key roles in maintaining genomic stability, eliminating mismatch bases and preventing both mutagenesis in the short term and cancerogenesis in the long term. Polymorphisms of MLH1 in individuals may have an effect on the DNA repair capacity and therefore on cancer risk. Recently, emerging studies have been done to evaluate the association...

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Source

Identifiers

PMID: 21745804
DOI: 10.1093/mutage/ger032

Genes

MLH1

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The association between MLH1 -93 G>A polymorphism of DNA mismatch repair and cancer susceptibility: a meta-analysis.PMID 21745804Read ↗

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