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Article

Association between MutL homolog 1 polymorphisms and the risk of colorectal cancer: a meta-analysis.

Journal of cancer research and clinical oncology - 1 Dec 2015

Chen Haiyan, Shen Zhujing, Hu Yeting, Xiao Qian, Bei Dikai, Shen Xiangfeng, Ding Kefeng

Abstract excerpt

PURPOSE: As one of the most essential components of mismatch repair system, MutL homolog 1 (MLH1) plays an increasingly implicated role in initiation and promotion of colorectal carcinogenesis, with germ-line mutations in different loci. However, whether a single genetic variant in MLH1 could predict the risk of cancer was still under doubt and recent studies yielded inconsistent results. Therefore, this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25986311
DOI: 10.1007/s00432-015-1976-4

Genes

MLH1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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