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Article

Influence of genetic variants in type I interferon genes on melanoma survival and therapy.

PloS one - 1 Jan 2012

Lenci Romina Elizabeth, Bevier Melanie, Brandt Andreas, Bermejo Justo Lorenzo, Sucker Antje, Moll Iris, Planelles Dolores, Requena Celia, Nagore Eduardo, Hemminki Kari, Schadendorf Dirk, Kumar Rajiv

Abstract excerpt

Melanoma is an immunogenic tumor; however, the efficacy of immune-therapy shows large inter-individual variation with possible influence of background genetic variation. In this study we report the influence of genetic polymorphisms in the type I interferon gene cluster on chromosome 9p22 on melanoma survival. We genotyped 625 melanoma patients recruited in an oncology center in Germany for 44 polymorphisms...

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Identifiers

PMID: 23209811
DOI: 10.1371/journal.pone.0050692
PMCID: PMC3507747

Genes

IFNW1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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