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Article

Association of cytokine gene polymorphisms with malignant melanoma in Caucasian population.

Cancer immunology, immunotherapy : CII - 1 Mar 2007

Nikolova Penka N, Pawelec Graham P, Mihailova Snejina M, Ivanova Milena I, Myhailova Anastassia P, Baltadjieva Daniela N, Marinova Daniela I, Ivanova Svetlomira S, Naumova Elissaveta J

Abstract excerpt

It has been hypothesized that polymorphisms expected to result in functional changes in cytokine genes may influence susceptibility to cancer, including malignant melanoma (MM). Here, we have screened 24 potentially functional polymorphisms in five cytokine genes by PCR-SBT and PCR-SSP methods in 122 MM cell lines derived from Caucasian patients. The polymorphic positions studied were: TNFA -1031, -863, -857,...

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Identifiers

PMID: 16835788
DOI: 10.1007/s00262-006-0193-z
PMCID: PMC11029850

Genes

IFNG
TGFB1
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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