Article
Interleukin-10, interleukin-6 and interferon-gamma gene polymorphisms in melanoma patients.
Melanoma research - 1 Oct 2002
Martínez-Escribano J A, Moya-Quiles M R, Muro M, Montes-Ares O, Hernández-Caselles T, Frías J F, Alvarez-López M R
Abstract excerpt
The immune response against melanoma can be influenced by cytokines with potentially opposite effects on tumour cell growth, such as interleukin-10 (IL10), interleukin-6 (IL6) and interferon-gamma (IFNgamma). Our objective in this study was to investigate whether polymorphisms in the regulatory regions of IL10, IL6 and IFNgamma genes are associated with the development of primary cutaneous melanoma and/or the...
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